How Can Catalysis Be Exploited for Therapeutic Interventions?
The understanding of catalytic processes in pathogen defense has led to the development of novel therapeutic strategies. For example, enzyme replacement therapy can be used to enhance the activity of deficient or dysfunctional enzymes in patients with chronic infections. Additionally, the design of small-molecule enzyme inhibitors can disrupt the metabolic pathways of pathogens, rendering them more susceptible to immune clearance.