Yes, the sensitivity of a catalyst to functional groups can often be tuned:
Ligand Modification: Changing the ligands in a metal complex catalyst can alter its sensitivity to functional groups. Support Material: Changing the support material in heterogeneous catalysts can affect the interaction with functional groups. Temperature and Pressure: These conditions can be optimized to favor the interaction with specific functional groups. Solvents: Solvent choice can significantly influence the interaction between functional groups and the catalyst.
