Despite its advantages, microwave assisted synthesis does come with certain challenges: 1. Equipment Costs: High-quality microwave reactors can be expensive. 2. Scale-Up Issues: The technique is often easier to implement at a laboratory scale than in large-scale industrial processes. 3. Uniformity Concerns: Achieving uniform heating in larger volumes can be challenging. 4. Reaction Control: Some reactions can be too rapid under microwave conditions, making precise control difficult.
