There are several reasons why DMSO is often chosen as a solvent in catalytic reactions:
1. Polarity: DMSO has a high dielectric constant, making it a very polar solvent. This enhances the solubility of ionic and polar substrates and reagents. 2. Aprotic Nature: Being an aprotic solvent, DMSO does not donate hydrogen bonds, which can be advantageous in reactions where hydrogen bond donation would interfere. 3. Stability: DMSO is chemically stable under a wide range of conditions, including high temperatures and various pH levels. 4. Low Toxicity: Compared to other polar aprotic solvents, DMSO is relatively non-toxic, making it safer for laboratory and industrial use.
