The cell cycle is a tightly regulated process that ensures proper cell division and replication. CDKs are pivotal in controlling the progression of the cell cycle through its various phases (G1, S, G2, and M). For instance, CDK1, when complexed with cyclin B, regulates the transition from G2 phase to mitosis, while CDK4 and CDK6, in association with cyclin D, govern the G1 phase progression.