What Types of Reactions Can Ethyl Diazoacetate Undergo?
EDA can undergo several types of reactions when catalyzed, including:
Cyclopropanation: This is a key reaction where a carbene generated from EDA reacts with alkenes to form cyclopropanes. C–H Insertion: The carbene can insert into C–H bonds, allowing for the functionalization of hydrocarbons. Ylide Formation: EDA can react with phosphines to form phosphonium ylides, which are useful intermediates in the Wittig reaction. X–H Insertion: Carbenes from EDA can also insert into heteroatom-H bonds, such as O–H, N–H, and S–H, expanding the range of functionalization possibilities.
