The Haldane equation is derived from the Michaelis-Menten equation and describes the equilibrium between substrates and products in an enzyme-catalyzed reaction. It can be expressed as:
Where: - \( K_{eq} \) is the equilibrium constant. - \( k_{cat} \) is the catalytic constant (turnover number) for the forward reaction. - \( k_{-cat} \) is the catalytic constant for the reverse reaction. - \( K_{m} \) is the Michaelis constant for the forward reaction. - \( K_{-m} \) is the Michaelis constant for the reverse reaction.
