Single Particle Inductively Coupled Plasma Mass Spectrometry (spICP-MS) is an analytical technique that combines the capabilities of ICP-MS with the ability to analyze individual nanoparticles. It allows for the quantification and characterization of nanoparticles by measuring their elemental composition and size distribution. This technique is particularly significant in the field of catalysis for its ability to analyze nanostructured catalysts at the single-particle level.