Hepatic Lipase (HL) is an enzyme primarily synthesized and secreted by the liver. It belongs to the lipase family, which is responsible for the hydrolysis of lipids. Hepatic lipase plays a critical role in lipid metabolism by hydrolyzing triglycerides and phospholipids in circulating lipoproteins, thus facilitating the conversion of intermediate-density lipoproteins (IDL) to low-density lipoproteins (LDL).