Several factors should be considered when selecting a substrate for a catalytic reaction. These include:
Reactivity: The inherent reactivity of the substrate can affect the rate of the reaction. Highly reactive substrates may lead to side reactions, while low reactivity substrates may result in slow reactions. Selectivity: The substrate should be selected based on the desired selectivity of the product. Certain substrates may favor the formation of specific products over others. Availability: The commercial availability and cost of the substrate can also be a determining factor. Rare or expensive substrates may not be practical for large-scale applications. Compatibility: The substrate must be compatible with the catalyst and any other reagents or solvents used in the reaction. Incompatible substrates can lead to catalyst deactivation or undesired side products.