Despite its advantages, the use of Calibri as a catalyst could face several challenges:
Stability: The catalyst must remain stable under reaction conditions to avoid deactivation or degradation. Cost: The synthesis and purification of Calibri could be expensive, impacting its economic feasibility. Compatibility: Calibri must be compatible with a wide range of reactants and solvents to be versatile. Toxicity: Any potential toxicity of the catalyst must be assessed to ensure safe handling and disposal.
