While dppe is highly effective, it does have some limitations:
- Sensitivity to Air and Moisture: dppe-metal complexes can be sensitive to air and moisture, requiring inert conditions for handling and storage. - High Cost: The synthesis and purification of dppe can be expensive, which may limit its use in large-scale industrial applications. - Limited Solubility: dppe and its complexes may have limited solubility in certain solvents, which can restrict their applicability in some catalytic systems.
