ion exchange chromatography

What Are the Key Parameters to Consider in Ion Exchange Chromatography?

Several critical parameters can influence the efficiency and resolution of ion exchange chromatography:
- pH of the mobile phase: The pH can affect the charge of both the stationary phase and the analytes, influencing their interaction.
- Ionic strength: Increasing the ionic strength of the mobile phase can help elute strongly bound ions from the column.
- Flow rate: The speed at which the mobile phase travels through the column can impact separation quality.

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