Toxicity: Exposure to toxic catalysts or intermediates can cause acute or chronic health effects, including respiratory issues, skin irritation, and even carcinogenic effects. Flammability: Many catalysts and reactants are flammable or explosive, posing fire and explosion hazards. Corrosivity: Corrosive chemicals can damage equipment, infrastructure, and pose risks to human health through skin contact or inhalation. Reactivity: Some chemicals may react violently when mixed, leading to dangerous situations such as runaway reactions or toxic gas releases. Environmental Impact: Improper disposal or accidental release of chemicals can lead to environmental pollution, impacting soil, water, and air quality.