What are the Challenges in Using Pyridines in Catalysis?
Despite their advantages, there are some challenges associated with using pyridines in catalysis: - Sensitivity: Pyridine-based catalysts can be sensitive to air and moisture, requiring careful handling and storage. - Toxicity: Some pyridine compounds can be toxic, necessitating proper safety measures during their use and disposal. - Complexity: Designing pyridine-based ligands with specific properties can be complex, requiring a deep understanding of coordination chemistry and catalysis.