What Are the Challenges in Using Cyclodextrins in Catalysis?
Despite their numerous advantages, there are also challenges associated with the use of cyclodextrins in catalysis. One of the main challenges is the limited size of their cavity, which restricts the range of substrates that can be effectively encapsulated. Additionally, the formation of inclusion complexes can sometimes be slow or incomplete, affecting the overall efficiency of the catalytic process. Overcoming these challenges often involves the design and synthesis of modified cyclodextrins with tailored properties.