Despite the advantages, there are several challenges associated with nanoscale catalysis. These include:
1. Stability: Nanoscale catalysts can be prone to agglomeration, which reduces their effective surface area and catalytic activity. 2. Scalability: Producing nanoscale catalysts on an industrial scale can be challenging and costly. 3. Environmental and Health Concerns: The potential toxicity and environmental impact of nanoscale materials need to be thoroughly evaluated.