What Are the Challenges Associated with Time-Resolved X-ray Crystallography?
Despite its powerful capabilities, time-resolved X-ray crystallography faces several challenges: - Crystal Quality: High-quality crystals that can withstand intense X-ray exposure are essential. - Time Resolution: Achieving high time resolution to capture fast reactions requires advanced synchronization. - Data Interpretation: Interpreting the data to distinguish between different intermediate states can be complex. - Sample Damage: X-ray exposure can cause radiation damage to the crystals, complicating data collection.