dynamic combinatorial chemistry

What are the Challenges Associated with DCC in Catalysis?

While DCC offers several advantages, there are also challenges that need to be addressed:
Reversibility of Reactions: The success of DCC depends on the reversibility of the chemical reactions used to create the library. Not all reactions are reversible under standard conditions.
Complexity of Analysis: The dynamic nature of the system can make it difficult to isolate and identify the active catalyst species.
Thermodynamic vs. Kinetic Control: The system typically favors thermodynamically stable species, which may not always be the most kinetically efficient catalysts.

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