NHCs are utilized in a variety of catalytic processes:
Cross-Coupling Reactions: NHCs are commonly employed in Suzuki-Miyaura, Heck, and Sonogashira couplings, providing high activity and selectivity. Olefin Metathesis: NHC-based catalysts are crucial for Grubbs and Schrock metathesis reactions, enabling the formation of complex molecular architectures. Hydrogenation: NHCs stabilize active metal centers in hydrogenation catalysts, enhancing their efficiency and selectivity. Asymmetric Catalysis: Chiral NHCs are employed in enantioselective reactions, providing high enantioselectivity and yield.
