What are the Advantages of Buchwald-Hartwig Amination?
Buchwald-Hartwig amination offers several advantages: 1. Versatility: It can be used with a wide range of aryl halides and amines. 2. Mild Conditions: The reaction often proceeds under relatively mild conditions, preserving sensitive functional groups. 3. High Selectivity: The use of specific ligands can enhance the selectivity towards desired products.