What Are Some Key Enzymes Involved in RNA Cleavage?
Several ribonucleases play crucial roles in RNA cleavage, including RNase A, RNase H, and Dicer. RNase A cleaves single-stranded RNA at the 3'-end of pyrimidine nucleotides. RNase H specifically degrades the RNA strand of RNA-DNA hybrids, which is vital for processes like DNA replication and repair. Dicer is involved in the processing of double-stranded RNA into small interfering RNA (siRNA) and microRNA (miRNA), which are essential for gene regulation.
