What Are Some Challenges Associated with Solid State NMR?
Despite its advantages, solid state NMR also faces several challenges: - Sensitivity: Solid state NMR is generally less sensitive compared to solution NMR, requiring larger sample sizes and longer acquisition times. - Resolution: The spectra can be complex and overlapping, especially for materials with heterogeneous structures. - Instrumental Requirements: Solid state NMR requires specialized equipment such as high-field magnets and magic angle spinning (MAS) probes, which can be expensive and require skilled operation.