Enzymes are classified into six major categories based on the type of reaction they catalyze: 1. Oxidoreductases: Catalyze oxidation-reduction reactions. 2. Transferases: Transfer functional groups from one molecule to another. 3. Hydrolases: Catalyze the hydrolysis of various bonds. 4. Lyases: Add or remove groups from substrates without hydrolysis or oxidation. 5. Isomerases: Catalyze isomerization changes within a molecule. 6. Ligases: Catalyze the joining of two molecules with the concomitant hydrolysis of a diphosphate bond.