The activity of the sodium potassium pump is regulated by several factors: - Ion Concentration: The availability of sodium and potassium ions influences the pump’s activity. - ATP Levels: Sufficient ATP is required for the pump to function. - Hormones: Hormones like aldosterone can increase the number of pump molecules in the cell membrane, enhancing activity. - Phosphorylation and Dephosphorylation: Cellular signaling pathways that lead to phosphorylation or dephosphorylation of the pump can modulate its activity.