How is Histone Modification Related to Chromatin Remodeling?
Histone modifications such as acetylation, methylation, phosphorylation, and ubiquitination can either facilitate or hinder chromatin remodeling. These modifications serve as signals that recruit or repel chromatin remodelers. For example, acetylation of histone tails generally leads to a more relaxed chromatin structure, allowing easier access for transcription factors and other DNA-binding proteins.
