Centrality can be measured using various metrics, including: - Degree Centrality: The number of connections a node has in a reaction network. - Betweenness Centrality: The frequency a node appears on the shortest path between other nodes. - Closeness Centrality: The average length of the shortest path from a node to all other nodes in the network. - Eigenvector Centrality: The influence of a node based on the importance of its neighbors.