How Does TFIIF Interact with Other Transcription Factors?
TFIIF interacts with various other transcription factors such as TFIIB, TFIIE, and TFIIH. These interactions are essential for the assembly of the pre-initiation complex (PIC). TFIIF binds to RNA polymerase II and TFIIB, aiding in the recruitment of the polymerase to the promoter. Additionally, its association with TFIIE and TFIIH is crucial for the subsequent steps of transcription initiation, including promoter melting and the transition from initiation to elongation.
