How Does Catalysis Influence Epigenetic Regulation?
Epigenetic regulation involves changes in gene expression that do not alter the DNA sequence but can be inherited. Enzymes are pivotal in epigenetic modifications. For example, DNA methyltransferases add methyl groups to DNA, and histone acetyltransferases modify histones, affecting how tightly DNA is wound around histones and thereby influencing gene expression. These enzymatic modifications can activate or repress gene transcription.