Isotope tracers are used in various ways in catalysis research:
- Reaction Mechanism Studies: By incorporating isotopes into reactants, researchers can observe how these atoms move through a reaction. For example, by using 18O in a water molecule, scientists can track oxygen atoms and determine if they are incorporated into the product or released as a by-product. - Kinetic Isotope Effect (KIE): This involves comparing the reaction rates of isotopically labeled and unlabeled compounds. A significant difference in rates can provide insights into the rate-determining step of a reaction. - Intermediates Identification: Isotope tracers can help identify transient intermediates that are otherwise difficult to detect. By observing the isotopic composition of intermediates, researchers can deduce their structure and role in the catalytic cycle.
