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How Are Intermediates Detected?

Detecting intermediates often requires advanced analytical techniques due to their transient nature. Some common methods include:
Spectroscopy: Techniques like UV-Vis, IR, NMR, and EPR spectroscopy can provide information about the presence and structure of intermediates.
Mass Spectrometry: This technique can detect and identify intermediates based on their mass-to-charge ratio.
X-ray Diffraction: Useful for studying the structure of intermediates in solid-state catalysis.
Computational Methods: Theoretical calculations and simulations can predict the existence and properties of intermediates.

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