Can Catalysts Be Used to Enhance LDL Receptor Activity?
Research is ongoing to develop therapeutic strategies that can enhance LDL receptor activity. Statins, for example, are drugs that inhibit the enzyme HMG-CoA reductase, leading to increased expression of LDL receptors on the cell surface. This enhances the clearance of LDL particles from the bloodstream. Additionally, PCSK9 inhibitors are a class of drugs that prevent the degradation of LDL receptors, thereby increasing their availability and function.
