Miguel Alcalde - Catalysis

Author Information

Miguel Alcalde is a prominent researcher affiliated with the Department of Biocatalysis at the Institute of Catalysis, CSIC, located in Cantoblanco, Madrid, Spain. His research primarily focuses on enzymatic catalysis, with a particular emphasis on fungal peroxygenases and peroxidases. His work involves the engineering of these enzymes for various applications, including oxyfunctionalization chemistry and the degradation of complex organic compounds.

Research Contributions

Miguel Alcalde has made significant contributions to the field of catalysis, particularly in the engineering and functionalization of fungal enzymes. In 2022 alone, he has published several impactful papers, including work on the engineering of fungal unspecific peroxygenases and the design of stable and functionally diverse versatile peroxidases. His research also explores innovative biocatalytic processes, such as the transformation of ethylbenzene derivatives into enantioenriched phenylethanols and the development of high-throughput screening assays for enzyme engineering. His earlier work in 2021 includes studies on the biocatalytic aromaticity-breaking epoxidation of naphthalene, ether oxidation by evolved fungal heme-peroxygenase, and the functional expression of unusual acidic peroxygenases from Candolleomyces aberdarensis.

Aliases

Miguel Alcalde is also known by several aliases, including M Alcalde and M. Alcalde.

Publication and Citation Metrics

Metric	Value
Citation Count	8306
h-index	49
Paper Count	189

Publications:

Surfing the wave of oxyfunctionalization chemistry by engineering fungal unspecific peroxygenases.

DOI: 10.1016/j.sbi.2022.102342

Year: 2022

Stable and Functionally Diverse Versatile Peroxidases Designed Directly from Sequences

DOI: 10.1021/jacs.1c12433

Year: 2022

A Peroxygenase‐Alcohol Dehydrogenase Cascade Reaction to Transform Ethylbenzene Derivatives into Enantioenriched Phenylethanols

DOI: 10.1002/cbic.202200017

Year: 2022

Colorimetric High-Throughput Screening Assay to Engineer Fungal Peroxygenases for the Degradation of Thermoset Composite Epoxy Resins

DOI: 10.3389/fctls.2022.883263

Year: 2022

Biocatalytic Aromaticity-Breaking Epoxidation of Naphthalene and Nucleophilic Ring-Opening Reactions

DOI: 10.1021/acscatal.0c05588

Year: 2021

Ether Oxidation by an Evolved Fungal Heme-Peroxygenase: Insights into Substrate Recognition and Reactivity

DOI: 10.3390/jof7080608

Year: 2021

Directing Evolution of the Fungal Ligninolytic Secretome

DOI: 10.1002/9783527815128.ch12

Year: 2021

Functional Expression of Two Unusual Acidic Peroxygenases from Candolleomyces aberdarensis in Yeasts by Adopting Evolved Secretion Mutations

DOI: 10.1128/AEM.00878-21

Year: 2021

A modular two yeast species secretion system for the production and preparative application of unspecific peroxygenases

DOI: 10.1038/s42003-021-02076-3

Year: 2021

Corrigendum: Mapping Potential Determinants of Peroxidative Activity in an Evolved Fungal Peroxygenase From Agrocybe aegerita

DOI: 10.3389/fbioe.2021.778727

Year: 2021

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