Isothermal Titration Calorimetry (ITC) is a powerful and versatile analytical technique used to measure the thermodynamics of interactions in solution. In the context of Catalysis, ITC allows researchers to determine the binding affinity, stoichiometry, and thermodynamic parameters such as enthalpy (ΔH), entropy (ΔS), and the Gibbs free energy (ΔG) of a catalytic reaction.