What Are the Challenges and Limitations of SERS in Catalysis?
Despite its advantages, SERS also has some challenges and limitations:
Reproducibility: Achieving consistent enhancement factors across different SERS substrates can be challenging. Substrate Preparation: The fabrication of high-quality, reproducible SERS substrates requires precise control over nanostructure size and morphology. Interference: Strong fluorescent backgrounds or other interfering signals can complicate the interpretation of the Raman spectra. Surface Selectivity: SERS primarily probes molecules near the metal surface, which may not fully represent the bulk catalytic process.
