Catalysis is integral to the [drug discovery]() and development process. High-throughput screening techniques utilize catalytic assays to identify potential antibiotic candidates from large chemical libraries. Additionally, [catalytic promiscuity](), where enzymes catalyze multiple reactions, is exploited to create novel antibiotic structures. Advances in [biocatalysis]() and [chemoenzymatic synthesis]() enable the development of new antibiotics with improved properties and reduced resistance potential.