How Do Geometric Isomers Affect Catalytic Activity?
The geometric configuration can influence the approach and binding of substrates to the active site of the catalyst. For instance, a cis isomer might fit better into the catalytic site compared to its trans counterpart, leading to enhanced catalytic activity. This is particularly important in enantioselective catalysis, where the geometry of the substrate can determine the formation of one enantiomer over another.
