Fructose 2,6 Bisphosphate - Catalysis

Relevant Publications

Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington\'s disease.

Issue Release: 2024

TIGAR Deficiency Blunts Angiotensin-II-Induced Cardiac Hypertrophy in Mice.

Issue Release: 2024

Drug-repurposing by virtual and experimental screening of PFKFB3 inhibitors for pancreatic cancer therapy.

Issue Release: 2024

F2,6BP restores mitochondrial genome integrity in Huntington\'s Disease.

Issue Release: 2024

PFKFB3 protein in adipose tissue contributes to whole body glucose homeostasis.

Issue Release: 2024

Exploring cell cycle-mediated regulations of glycolysis in budding yeast.

Issue Release: 2023

Metabolic priming in G6PDH isoenzyme-replaced tobacco lines improves stress tolerance and seed yields via altering assimilate partitioning.

Issue Release: 2023

Combination of 3PO analog PFK15 and siPFKL efficiently suppresses the migration, colony formation ability, and PFK-1 activity of triple-negative breast cancers by reducing the glycolysis.

Issue Release: 2023

Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.

Issue Release: 2023

A glycolytic metabolite restores DNA repair activity of polynucleotide kinase 3\'-phosphatase in polyglutamine (PolyQ) diseases.

Issue Release: 2023

Transcriptome profiling reveals the underlying mechanism of grape post-harvest pathogen against the metabolites of .

Issue Release: 2023

PFKFB3 Increases IL-1 and TNF- in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer.

Issue Release: 2022

Revisited Metabolic Control and Reprogramming Cancers by Means of the Warburg Effect in Tumor Cells.

Issue Release: 2022

Treatment against glucose-dependent cancers through metabolic PFKFB3 targeting of glycolytic flux.

Issue Release: 2022

Targeting Resistance in Medulloblastoma.

Issue Release: 2022

PFKFB3 Regulates Chemoresistance, Metastasis and Stemness IAP Proteins and the NF-κB Signaling Pathway in Ovarian Cancer.

Issue Release: 2022

Fructose-6-phosphate-2-kinase/Fructose-2,6-bisphosphatase Regulates Energy Metabolism and Synthesis of Storage Products in Developing Rice Endosperm.

Issue Release: 2022

A high-throughput screening campaign against PFKFB3 identified potential inhibitors with novel scaffolds.

Issue Release: 2022

Knockout of TIGAR enhances myocardial phosphofructokinase activity and preserves diastolic function in heart failure.

Issue Release: 2022

Therapeutic targeting of PFKFB3 and PFKFB4 in multiple myeloma cells under hypoxic conditions.

Issue Release: 2022

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